Anti-RPH3AL Polyclonal Antibody for WB, IF/ICC, ELISA - Q9UNE2

Core Product Specifications and Parameters

Biological Background: RPH3AL Function and Localization

• RPH3AL encodes the Rab effector Noc2, also known as No C2 domains protein or Rabphilin-3A-like protein, which functions as a Rab GTPase effector.
• This protein is involved in the late steps of regulated exocytosis in both endocrine and exocrine cells, acting as a potential RAB3B effector in epithelial cells.
• RPH3AL is localized to the cytoplasm and associates with the membrane of cytoplasmic and secretory vesicles, consistent with its role in vesicle trafficking.
• The protein is expressed at moderate to high levels in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney, and liver, and is also detected in epithelial cells.
• RPH3AL contains a zinc-finger domain and requires zinc binding for its function; it is subject to alternative splicing.

Experimental Guidance and Technical Tips

• The immunogen covers amino acids 161-315 of human RPH3AL, a region that likely includes functional domains; consider using full-length controls to confirm specificity.
• For Western blotting, a band around 34kDa is expected; note that alternative splicing may produce additional isoforms.
• In immunofluorescence, anticipate a cytoplasmic and vesicular staining pattern; validate in relevant cell types with known RPH3AL expression.
• The antibody is reported to cross-react with mouse RPH3AL; verify reactivity in your species of interest using appropriate controls.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio streamlines the procurement of IVD raw materials, offering validated antibodies like this anti-RPH3AL polyclonal antibody for research in exocytosis and secretion pathways. From optimized monoclonal/polyclonal antibodies and bulk ancillary reagents to rare-target raw-material sourcing, we support diagnostic manufacturers and labs from concept to clinic. Explore our catalog to accelerate your RPH3AL-related projects with reliable supply and technical support.