Anti-ROMO1 Rabbit Monoclonal Antibody for WB - P60602

Core Product Specifications and Parameters

Biological Background: ROMO1 Function and Localization

• ROMO1 (Reactive oxygen species modulator 1), also known as MTGM, Glyrichin, or Protein MGR2 homolog, is a mitochondrial inner membrane protein.
• It induces the production of reactive oxygen species (ROS) that are necessary for cell proliferation and may promote oxidative DNA damage and replicative senescence.
• ROMO1 is involved in coordinating mitochondrial morphology with cell proliferation.
• The protein exhibits antibacterial activity against a broad spectrum of bacteria, including S. aureus, P. aeruginosa, and M. tuberculosis, by inducing membrane breakage.
• Tissue specificity: ROMO1 is upregulated in multiple cancer cell lines compared to normal fibroblasts and is highly expressed in brain tumors.
• Keywords associated with ROMO1 include alternative splicing, antibiotic, antimicrobial, transmembrane, and mitochondrion inner membrane.

Experimental Guidance and Technical Tips

• The immunogen was designed against amino acids 1–79 of human ROMO1, covering the full-length protein. This region may be suitable for detecting total ROMO1 levels.
• For western blotting, note the low molecular weight (~8 kDa); optimize gel percentage and transfer conditions to resolve small proteins.
• When using immunofluorescence or immunohistochemistry, consider co‑staining with a mitochondrial marker to confirm localization.
• Validate antibody specificity in the relevant sample system, especially if using applications such as IF/ICC or IHC-P on tissue sections.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers and research laboratories a streamlined channel for procuring validated IVD raw materials, including monoclonal antibodies like this anti-ROMO1 clone. With expertise in mitochondrial biology and ROS-related targets, we provide access to optimized antibody pairs, bulk ancillary reagents, and customized rare‑target sourcing to support your assay development and scaling needs.