Anti-RBP4 Polyclonal Antibody for WB, ELISA - P02753

Core Product Specifications and Parameters

Biological Background: RBP4 Function and Localization

• RBP4 (retinol-binding protein 4), also known as plasma retinol-binding protein (PRBP), is encoded by the RBP4 gene in humans.
• Mediates retinol transport in blood plasma, delivering retinol from liver stores to peripheral tissues. Related references: PMID:5541771
• Transfers bound all-trans retinol to the STRA6 receptor, facilitating retinol uptake across cell membranes. Related references: PMID:22665496
• Secreted protein detected in blood plasma and urine.
• Contains a retinol-binding domain and a disulfide bond; undergoes post-translational methylation.
• Associated with vitamin A metabolism, vision, and sensory transduction.
• Structural studies are available; genetic variants are linked to microphthalmia and other eye disorders.

Experimental Guidance and Technical Tips

• Given the secreted nature of RBP4, consider using serum or plasma samples for WB analysis; validate detection in your specific sample matrix.
• The immunogen spans nearly the entire mature protein (aa 19-201), likely recognizing full-length RBP4; verify performance under both reducing and non-reducing conditions if needed.
• Cross-reactivity with mouse and rat makes this antibody suitable for rodent models; confirm reactivity in your target species.
• For ELISA, optimize coating and detection conditions and consider pairing with another RBP4 antibody if a sandwich assay is desired.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers a streamlined procurement channel for IVD raw materials, connecting diagnostic developers with validated antibodies, bulk ancillary reagents, and rare target sourcing. Whether you need ready-to-use RBP4 antibody pairs, high-performance polyclonal antibodies, or custom raw-material support for retinol transport research, we can help accelerate your development from concept to clinic.