Anti-RBM26 Rabbit Polyclonal Antibody for WB and ELISA - Q5T8P6

Core Product Specifications and Parameters

Biological Background: RBM26 Function and Localization

• RBM26, also known as SE70-2, ZC3H17, and others, is an RNA-binding protein that contains zinc-finger domains and coiled-coil regions.
• It may participate in the regulation of nuclear polyadenylated (pA+) RNA turnover, suggesting a role in post-transcriptional gene expression control.
• The protein is subject to multiple post-translational modifications, including acetylation, phosphorylation, and ubiquitination, which may modulate its activity.
• Alternative splicing of the RBM26 gene generates multiple isoforms, potentially expanding its functional diversity.
• RBM26 is classified as a reference proteome component and has been identified in high-throughput proteomics studies.
• The presence of metal-binding and zinc-finger motifs indicates that RBM26 may interact with nucleic acids or other proteins in a zinc-dependent manner.

Experimental Guidance and Technical Tips

• The immunogen spans amino acids 65–140 of human RBM26, which may target a region critical for antibody specificity. Consider performing epitope mapping if precise binding information is required.
• For Western blot, use whole-cell lysates from human cell lines expressing RBM26; the predicted molecular weight is approximately 114 kDa. Ensure proper sample preparation and loading controls.
• In ELISA applications, the antibody can be used for direct antigen detection. Optimal coating concentrations and incubation conditions should be empirically determined for each assay system.
• Cross-reactivity is confirmed only for human RBM26; reactivity with orthologs from other species has not been evaluated. Validate in the relevant sample system if needed.

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CamelBio provides diagnostic manufacturers and research laboratories with a comprehensive selection of IVD raw materials, including validated antibody pairs and optimized monoclonal/polyclonal antibodies like this anti-RBM26 polyclonal antibody. Our one-stop sourcing solutions encompass bulk ancillary reagents and rare target raw-material procurement, streamlining your development workflow from concept to clinic. For RNA-binding protein research or post-transcriptional regulation studies, rely on CamelBio to bridge your supply needs efficiently.