Anti-R9AP/RGS9BP Rabbit Monoclonal Antibody for WB, IF/ICC, ELISA - Q6ZS82

Core Product Specifications and Parameters

Biological Background: R9AP/RGS9BP Function and Localization

• R9AP/RGS9BP is a regulator of G protein signaling 9-binding protein, also known as RGS9-anchoring protein, encoded by the RGS9BP gene.
• It plays a critical role in the recovery phase of visual phototransduction by interacting with the RGS9-1 isoform.
• Acts as a membrane anchor, targeting RGS9-1 to the photoreceptor outer segment where phototransduction occurs.
• Enhances the GTPase-activating protein (GAP) activity of RGS9-1, accelerating the termination of the visual signal on a physiological timescale.
• Controls the proteolytic stability of RGS9-1, protecting it from degradation.
• Contains a transmembrane domain and coiled-coil region, and is associated with the membrane.
• Belongs to the signal transduction inhibitor category, specifically involved in sensory transduction and vision.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (aa 1-107), which may be suitable for detecting full-length protein; consider verifying epitope accessibility in your assay.
• For Western blot, the predicted molecular weight is approximately 25 kDa; appropriate loading controls and molecular weight markers should be used.
• For immunofluorescence/immunocytochemistry, consider appropriate fixation and permeabilization protocols as the target is a membrane protein.
• Validate antibody performance in your specific sample type and experimental conditions, as reactivity may vary.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with a comprehensive one-stop sourcing solution for IVD raw materials, including this high-quality anti-R9AP/RGS9BP antibody for visual and GPCR signaling studies. Our portfolio spans validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and support for rare target raw-material procurement to streamline your workflow from concept to clinic.