Anti-PYCR1 Rabbit Polyclonal Antibody for WB, ELISA - P32322

Core Product Specifications and Parameters

Biological Background: PYCR1 Function and Localization

• Encodes pyrroline-5-carboxylate reductase 1, a mitochondrial enzyme that catalyzes the last step in proline biosynthesis, reducing pyrroline-5-carboxylate to L-proline using NAD(P)H. Related references: PMID:16730026 | PMID:19648921 | PMID:23024808
• At physiologic concentrations, the enzyme preferentially utilizes NADH as a cofactor. Related references: PMID:16730026 | PMID:23024808
• Plays a role in the cellular response to oxidative stress. Related references: PMID:16730026 | PMID:19648921
• Localizes to the mitochondrion.
• Post-translationally modified by acetylation and phosphorylation.
• Alternative splicing generates multiple isoforms.
• Belongs to the pyrroline-5-carboxylate reductase family, involved in amino acid biosynthesis and stress response.

Experimental Guidance and Technical Tips

• This polyclonal antibody was raised against the full-length human PYCR1 recombinant protein; consider performing dilution optimization and using appropriate positive controls for WB.
• Cross-reactivity with mouse and rat makes it suitable for multispecies studies; validate expression in the relevant sample system.
• Due to its role in oxidative stress, PYCR1 expression may vary under different conditions; include appropriate experimental controls.

CamelBio: Your One-Stop Sourcing Bridge

For your PYCR1-related studies, CamelBio provides this anti-PYCR1 rabbit polyclonal antibody as part of a comprehensive IVD raw-material supply solution. We support proline metabolism and oxidative stress research with validated antibody pairs, bulk ancillary reagents, and custom sourcing of rare targets. Our expert team assists with procurement and seamless integration into your diagnostic and research workflows, ensuring a reliable supply chain from concept to clinic.