Anti-PLD2 Polyclonal Antibody for WB, ELISA - O14939

Core Product Specifications and Parameters

Biological Background: PLD2 Function and Localization

• PLD2 (Phospholipase D2), also known as Choline phosphatase 2 or PLD1C, is encoded by the PLD2 gene. Alternative splicing generates multiple isoforms.
• Functions as a phospholipase that hydrolyses phosphatidylcholine, playing a central role in lipid degradation and metabolism. Related references: PMID:9582313
• May participate in signal-induced cytoskeletal regulation and endocytosis (By similarity).
• Localizes to the cell membrane.
• Expressed ubiquitously across tissues.
• Classified as a hydrolase and a phosphoprotein; its keywords include lipid degradation, lipoprotein involvement, and repeat regions.

Experimental Guidance and Technical Tips

• In Western blot, expect a band at approximately 106 kDa; however, post-translational modifications may cause slight shifts. Validate detection in your sample system.
• The antibody detects human, mouse, and rat PLD2 based on cross reactivity data; optimization of experimental conditions is recommended for each species.
• For ELISA, consider pairing with a suitable capture antibody and using recombinant PLD2 (e.g., the immunogen) as a positive control.
• Pre-absorption with the immunogen may be used to confirm specificity in critical applications.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers, laboratories, and research institutes a seamless sourcing experience for IVD raw materials, including validated antibody pairs and bulk ancillary reagents. This anti-PLD2 polyclonal antibody supports investigations into phospholipase D2, lipid metabolism, and signal transduction. For specialized or large-scale requirements, CamelBio provides expert technical and sourcing assistance from concept to clinical application.