Anti-PEX11B Rabbit Monoclonal Antibody for WB, ELISA - O96011

Core Product Specifications and Parameters

Biological Background: PEX11B Function and Localization

• PEX11B is also known as Peroxin-11B, Peroxisomal biogenesis factor 11B, and Protein PEX11 homolog beta (PEX11-beta), encoded by the PEX11B gene.
• Involved in peroxisomal proliferation. Related references: PMID:9792670
• May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Related references: PMID:12618434
• Promotes membrane protrusion and elongation on the peroxisomal surface. Related references: PMID:20826455
• Localizes to the peroxisome membrane.
• The protein is subject to acetylation and alternative splicing, contains transmembrane helices, and mutations are associated with peroxisome biogenesis disorders.

Experimental Guidance and Technical Tips

• The immunogen used is a synthetic peptide corresponding to amino acids 50–150 of human PEX11B; the antibody may recognize epitopes within this region. Consider this when designing competition or peptide blocking experiments.
• For Western blot, the predicted molecular weight is 28 kDa; validate with appropriate positive controls (e.g., human cell lines expressing PEX11B) and optimize protein loading and transfer conditions.
• For ELISA, evaluate the antibody as a capture or detection reagent by titrating it in the relevant matrix and confirming specificity with recombinant PEX11B or peptide competition.

CamelBio: Your One-Stop Sourcing Bridge

As a comprehensive IVD raw-material supplier, CamelBio provides integrated access to optimized antibodies like this PEX11B rabbit monoclonal, along with validated antibody pairs, bulk ancillary reagents, and custom sourcing for rare targets in peroxisomal biology and beyond. Our one-stop model streamlines procurement from concept to clinic, supporting diagnostic manufacturers and research institutions with consistent quality and supply.