Anti-P2RY10 Rabbit Polyclonal Antibody for WB, ELISA - O00398

Core Product Specifications and Parameters

Biological Background: P2RY10 Function and Localization

• P2RY10, also known as P2Y-like receptor, LPS2, P2Y10, LYPSR2, is a putative G protein-coupled receptor for purines.
• The receptor is predicted to couple to G proteins, suggesting involvement in purinergic signaling pathways.
• It is localized to the cell membrane, consistent with its role as a transmembrane receptor.
• The protein is glycosylated and contains disulfide bonds, typical of GPCRs.
• Expression is weakly detected in blood leukocytes, implying a potential role in immune cell function.
• According to UniProt, the molecular weight is approximately 38.8 kDa (calculated), while observed at 39 kDa in product specifications.
• The receptor belongs to the P2Y purinoceptor family, which mediates diverse cellular responses to extracellular nucleotides.
• No other isoforms or splice variants are reported for human P2RY10.

Experimental Guidance and Technical Tips

• The immunogen targets the C-terminal region (amino acids 200 to end) of human P2RY10 (isoform NP_001311147.1), which may recognize the full-length protein in Western blotting.
• For WB, consider a 39 kDa band for P2RY10 and validate specificity using appropriate controls.
• For ELISA, the polyclonal antibody may be used to detect P2RY10 peptides or recombinant protein; titration is recommended.
• Cross-reactivity with mouse and rat is expected based on specifications, but verify in your experimental system.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides a comprehensive supply solution for IVD raw materials, including validated antibodies like this anti-P2RY10 polyclonal antibody, ideal for research into G protein-coupled purinergic receptors. We support diagnostic developers with bulk reagents, technical consultation, and sourcing of rare targets, streamlining your path from concept to clinic.