Anti-OXA1L Rabbit Polyclonal Antibody for WB and ELISA - Q15070

Core Product Specifications and Parameters

Biological Background: OXA1L Function and Localization

• OXA1L (OXA1Hs, oxidase assembly 1-like protein) is a mitochondrial inner membrane insertase that mediates cotranslational insertion of integral membrane proteins.
  Related references: PMID:17936786 PMID:33602856 PMID:7991568
• Essential for the activity and assembly of cytochrome oxidase.
  Related references: PMID:17936786 PMID:7991568
• Required for correct biogenesis of ATP synthase and complex I in mitochondria.
  Related references: PMID:17936786 PMID:7991568
• Localizes specifically to the mitochondrial inner membrane.
• Keywords: Alternative splicing, Membrane, Mitochondrion inner membrane, Phosphoprotein, Proteomics identification, Reference proteome, Transit peptide, Transmembrane, Transmembrane helix.
• The protein is subject to alternative splicing and phosphorylation, which may regulate its function.

Experimental Guidance and Technical Tips

• The immunogen spans the C-terminal region (amino acids 336–435) of human OXA1L, enabling detection of full-length endogenous protein in validated species (human, mouse, rat).
• For Western blot, expect a band near 49 kDa; we recommend using appropriate mitochondrial fractions or whole‑cell lysates with positive controls.
• While validated for WB and ELISA by the supplier, each protocol should be optimized for your experimental conditions. Consider titrating the antibody to reduce background.
• Due to high sequence conservation, cross‑reactivity with other species may be possible and should be verified experimentally.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio specializes in supplying IVD raw materials, offering a comprehensive portfolio that includes validated polyclonal and monoclonal antibodies, antigen or antibody pairs, and ancillary reagents for mitochondrial research targets like OXA1L. Whether you are scaling up assay development or sourcing rare‑target reagents, CamelBio provides a streamlined procurement experience backed by technical support to help move your project from concept to clinic.