Anti-OSR2 Polyclonal Antibody for WB, ELISA - Q8N2R0

Core Product Specifications and Parameters

Biological Background: OSR2 Function and Localization

• OSR2 is a zinc-finger protein belonging to the odd-skipped related family, characterized by C2H2-type zinc-finger domains that mediate DNA binding and transcriptional regulation.
• The protein may play a role in embryonic development, specifically in the formation of the mandibular molar tooth germ during the bud stage.
• OSR2 localizes predominantly to the nucleus, consistent with its function as a transcription factor.
• The OSR2 gene undergoes alternative splicing, yielding multiple isoforms that may have distinct regulatory properties.
• It is a metal-binding protein, requiring zinc ions for proper folding and function of its zinc-finger motifs.
• OSR2 has been identified in proteomics studies, supporting its expression in various human tissues.

Experimental Guidance and Technical Tips

• The immunogen is a synthetic peptide from the central region (aa 250–312) of human OSR2. For Western blot, consider using whole-cell lysates or nuclear extracts from human, mouse, or rat tissues/cells expressing OSR2.
• The predicted molecular weight is 36 kDa, but due to alternative splicing, multiple bands may be observed; validate specificity with appropriate controls.
• For ELISA, the antibody may be used as a capture or detection reagent; optimize coating and detection conditions empirically.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers a comprehensive one-stop sourcing solution for IVD raw materials, technical services, and consulting—from concept to clinic. For researchers studying developmental biology and zinc-finger transcription factors like OSR2, we provide validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and assistance with rare target raw-material sourcing.