Anti-OSR1 Rabbit Polyclonal Antibody for WB, IHC-P, ELISA - Q8TAX0

Core Product Specifications and Parameters

Biological Background: OSR1 Function and Localization

• OSR1, also known as odd-skipped-related 1 (ODD), is a transcription factor encoded by the OSR1 gene in humans.
• It functions in regulating embryonic development, particularly in the formation of the heart and urogenital system, through transcriptional control.
• OSR1 contains zinc-finger domains, classifying it as a zinc-finger transcription factor that binds DNA in a sequence-specific manner.
• The protein localizes predominantly to the nucleus, consistent with its role in transcription regulation.
• Tissue expression is observed in adult colon, small intestine, prostate, testis, and fetal lung, indicating potential roles in these organs.
• Post-translational modifications include methylation, which may modulate its activity; it is also identified as a metal-binding protein.
• As a member of the odd-skipped family, OSR1 is part of the proteomics identification reference proteome, highlighting its importance in biomedical research.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 28–115 of human OSR1; consider verifying full-length protein recognition in your specific assay.
• For WB, a band at ~30 kDa (predicted molecular weight) is expected; use a suitable loading control and pre-stained marker.
• In IHC-P, validate the antibody on tissues known to express OSR1 (e.g., colon, testis) and include appropriate negative controls.
• For ELISA, the recombinant immunogen fragment may serve as a positive control; assess cross-reactivity with closely related odd-skipped family members if needed.
• As a polyclonal antibody, lot-to-lot consistency should be monitored; always titrate the antibody for your own experimental conditions.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers and research laboratories with a comprehensive portfolio of IVD raw materials, including validated antibody pairs, optimized polyclonal antibodies like this anti-OSR1 reagent, and bulk ancillary reagents. Whether you are investigating developmental transcription factors or developing assays for urogenital or cardiac biomarkers, we bridge your sourcing needs from early-stage discovery to clinical application. Contact us for rare-target raw-material procurement and tailored technical support.