Anti-OR2T10 Rabbit Polyclonal Antibody for WB and ELISA - Q8NGZ9

Core Product Specifications and Parameters

Biological Background: OR2T10 Function and Localization

• OR2T10, also known as OR1-64, is a protein encoded by the OR2T10 gene in humans (Gene ID: 127069).
• It functions as an odorant receptor, mediating the detection of odorant molecules and initiating sensory transduction cascades involved in the sense of smell.
• OR2T10 belongs to the G protein-coupled receptor (GPCR) superfamily, which is characterized by seven transmembrane helices, and is part of the olfactory receptor family.
• The receptor is localized to the cell membrane, where it participates in the initial step of olfactory signal transduction upon odorant binding.
• It contains structural features typical of GPCRs, including disulfide bonds and glycosylation sites, which are important for proper folding, trafficking, and function.
• As a reference proteome member, OR2T10 is part of the curated human olfactory receptor repertoire, contributing to the diversity of odor perception.

Experimental Guidance and Technical Tips

• The immunogen, a synthetic peptide from the N‑terminal region (aa 1‑100) of human OR2T10, targets an extracellular domain; consider using peptide blocking to confirm specificity in detection assays.
• In WB, expect a band near the calculated 35‑kDa molecular weight, but olfactory receptors often need optimized membrane protein extraction and sample preparation due to their transmembrane nature.
• For ELISA, the peptide can be used as a coating antigen; testing in both direct and competitive formats is advised to evaluate antibody performance.
• Cross‑reactivity with mouse OR2T10 orthologs is reported; validate in mouse olfactory tissue or transfected cells to confirm recognition of the conserved target.
• Given that endogenous GPCR expression can be low, using positive controls such as transfected cell lines or recombinant protein is recommended for assay development.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers, laboratories, and research institutes comprehensive access to IVD raw materials, including validated antibodies for targets like OR2T10, supporting olfactory and GPCR‑focused research. Our supply chain spans antibody pairs, recombinant proteins, and ancillary reagents to accelerate your assay pipeline. With a commitment to quality sourcing, CamelBio bridges your needs from concept to clinic.