Anti-OR1A1 Rabbit Polyclonal Antibody for WB and ELISA - Q9P1Q5

Core Product Specifications and Parameters

Biological Background: Olfactory receptor 1A1 Function and Localization

• OR1A1 encodes olfactory receptor 1A1, a member of the G protein-coupled receptor (GPCR) superfamily involved in olfactory sensory transduction.
• The protein is also designated as olfactory receptor 17-7 (OR17-7) and OR17-11, functioning as an odorant receptor that detects volatile chemicals in the nasal epithelium.
• Subcellularly, OR1A1 is an integral membrane protein localized to the plasma membrane, consistent with its role in signal transduction.
• Characteristic structural features include seven transmembrane helices, essential for ligand binding and G protein activation.
• Post-translational modifications include N-linked glycosylation and disulfide bond formation, which are critical for receptor folding and stability.
• As a key component of the olfactory system, OR1A1 participates in the initial step of odor perception, converting chemical signals into electrical responses.
• Keywords: G protein-coupled receptor, olfaction, sensory transduction, transmembrane helix, glycoprotein, disulfide bond.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (amino acids 1–100), which may be exposed on the extracellular side; consider using membrane protein extraction protocols for optimal detection.
• For Western blot, the predicted molecular weight is approximately 35 kDa; note that glycosylation can cause a shift, so validate in the relevant sample system.
• This polyclonal antibody is suitable for ELISA; ensure coating buffer and blocking conditions are optimized for GPCR antigens.
• When working with olfactory or neuronal tissues, enriched membrane fractions can enhance signal specificity.
• As a polyclonal reagent, lot-to-lot consistency should be assessed when implementing in diagnostic assays.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides a comprehensive portfolio of IVD raw materials, including validated antibody pairs and optimized polyclonal antibodies like this anti-OR1A1 product, supporting manufacturers and researchers in olfactory and GPCR-targeted assay development. From rare target raw-material sourcing to bulk ancillary reagents, we offer a reliable, end-to-end supply chain to accelerate your diagnostic projects from concept to clinic.