Anti-Opticin (OPTC) Polyclonal Antibody for WB and ELISA - Q9UBM4

Core Product Specifications and Parameters

Biological Background: Opticin Function and Localization

• Opticin, also known as oculoglycan, is a member of the small leucine-rich repeat proteoglycan (SLRP) family.
• It inhibits angiogenesis in the vitreous humor of the eye, thereby repressing neovascularization.
• Opticin binds collagen fibrils and may regulate collagen fiber organization by modulating other SLRP members.
• The protein is secreted and localizes to the extracellular matrix of the vitreous humor and other tissues.
• Tissue expression includes cartilage, synovial membranes, retina, iris, ligament, skin, fetal liver, and retinal pigment epithelium. Related references: PMID:18164633 PMID:23845380 PMID:12019215 PMID:25136834
• Post-translational modifications include glycosylation and sulfation, and the protein contains disulfide bonds and leucine-rich repeats.

Experimental Guidance and Technical Tips

• The polyclonal nature of this antibody means it may recognize multiple epitopes, potentially enhancing signal in WB and ELISA.
• For Western blot, a specific band of approximately 37 kDa is expected; however, glycosylation may cause slight shifts in migration.
• Consider using the immunogen sequence (a.a. 20-115) when designing peptide competition assays to verify specificity.
• Cross-reactivity with mouse and rat suggests conserved epitopes, but always validate in the relevant species sample system.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop B2B partner for IVD raw materials, supporting diagnostic manufacturers and researchers from concept to clinic. This anti-Opticin polyclonal antibody is ideal for angiogenesis and extracellular matrix studies, with reliable cross-reactivity for murine models. Beyond this product, we offer validated antibody pairs, optimized monoclonal/polyclonal antibodies, and bulk ancillary reagents, plus rare target sourcing to streamline your assay development.