Anti-Olig3 Rabbit Monoclonal Antibody for WB, ELISA - Q7RTU3

Core Product Specifications and Parameters

Biological Background: Olig3 Function and Localization

• Olig3 is a basic helix-loop-helix (bHLH) transcription factor, also known as Class B basic helix-loop-helix protein 7 (bHLHb7) and Class E basic helix-loop-helix protein 20 (bHLHe20).
• It functions in neuronal specification within the dorsal spinal cord, promoting class A neuron identity and suppressing class B neuron differentiation.
• Olig3 contains a coiled-coil domain and a DNA-binding domain, typical of bHLH factors, enabling it to regulate target gene transcription.
• The protein localizes to the nucleus, consistent with its role as a transcription factor.
• According to UniProt keywords, Olig3 is involved in transcription regulation and DNA-binding, and is part of the reference proteome.

Experimental Guidance and Technical Tips

• The immunogen corresponds to a region within amino acids 173–272 of human Olig3, which may confer target specificity; validate in the relevant sample system.
• For Western blot, consider using lysates from human spinal cord tissue or neuronal cell lines; the predicted molecular weight is 29 kDa.
• For ELISA, the synthetic peptide may be used as a positive control to assess antibody binding performance.
• Cross-reactivity is indicated for human; reactivity with other species should be independently tested if needed.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, technical services, and consulting — from concept to clinic. This Olig3 antibody is part of our neuroscience portfolio, and we can supply validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and support rare target raw-material sourcing to accelerate your diagnostic development.