Anti-OCIAD1 Polyclonal Antibody for WB, IF/ICC, ELISA - Q9NX40

Core Product Specifications and Parameters

Biological Background: OCIAD1 Function and Localization

• OCIAD1 (OCIA domain-containing protein 1) is a 27626 Da protein encoded by the OCIAD1 gene. It exhibits alternative splicing: isoform 1 is highly expressed in testis, brain, placenta, ovary, prostate, and mammary gland, while isoform 2 is restricted to the central nervous system (brain, cerebellum, spinal cord).
• OCIAD1 maintains stem cell potency by increasing STAT3 phosphorylation and controlling ERK phosphorylation, likely through a scaffold mechanism that recruits STAT3 to endosomes (By similarity).
• OCIAD1 is involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer. Related references: PMID:20515946
• Subcellular localization studies indicate that OCIAD1 resides on endosomes, consistent with its role in endosomal signaling.
• Annotated keywords include alternative splicing, endosome, phosphoprotein, proteomics identification, and reference proteome.

Experimental Guidance and Technical Tips

• The immunogen used is a recombinant protein covering the full-length human OCIAD1 (aa1-245). Consider this when designing detection strategies.
• Validated for WB, IF/ICC, and ELISA applications. For IF/ICC, appropriate permeabilization may be required to access endosomal OCIAD1.
• Cross-reactivity with mouse and rat extends utility to rodent model systems. Validate antibody performance in the relevant sample system prior to use.
• OCIAD1 has multiple isoforms; confirm whether the antibody recognizes both isoforms based on your experimental needs.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio streamlines the procurement of IVD raw materials by offering validated antibody pairs, optimized polyclonal and monoclonal antibodies, bulk ancillary reagents, and rare-target sourcing. For researchers and diagnostic developers focusing on stem cell biology or ovarian cancer pathways, this anti-OCIAD1 antibody can be integrated into your assay development pipeline with reliable supply support.