Anti-NUP93 Rabbit Polyclonal Antibody for WB, ELISA - Q8N1F7

Core Product Specifications and Parameters

Biological Background: NUP93 Function and Localization

• NUP93 is a 93 kDa nucleoporin, also known as NIC96, encoded by the NUP93 gene (Gene ID: 9688).
• It is a key component of the nuclear pore complex (NPC) and plays a role in NPC assembly and/or maintenance. Related references: PMID:9348540
• May anchor nucleoporins to the NPC, excluding NUP153 and TPR.
• During renal development, NUP93 regulates podocyte migration and proliferation through SMAD4 signaling. Related references: PMID:26878725
• Subcellular localization: resides in the nuclear membrane, nuclear pore complex, and nuclear envelope.
• Molecular weight approximately 93 kDa; undergoes alternative splicing and phosphorylation.
• UniProt keywords indicate involvement in mRNA transport, protein transport, and association with disease variants.

Experimental Guidance and Technical Tips

• The immunogen corresponds to a recombinant protein spanning amino acids 670–819, a region likely to be accessible for antibody binding; consider using full-length NUP93 or lysates from relevant tissues as positive controls.
• For Western blot (WB), a band around 93 kDa is expected; validate antibody specificity using knockdown or knockout models where possible.
• This antibody has been reported to cross-react with human, mouse, and rat NUP93; confirm reactivity in your specific experimental system.
• ELISA applications may require optimization of coating antigen and antibody dilution; consider testing a dilution series against the immunogen or purified NPC fractions.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers and research labs a one-stop platform for IVD raw material procurement, covering the NUP93 target for nuclear pore complex and podocyte biology studies. Our portfolio includes validated antibody pairs, optimized polyclonal and monoclonal antibodies, bulk ancillary reagents, and specialized sourcing for rare targets. Let CamelBio streamline your supply chain from concept to clinic.