Anti-NUP160 Rabbit Polyclonal Antibody for WB, ELISA - Q12769

Core Product Specifications and Parameters

Biological Background: NUP160 Function and Localization

• Nup160 is a core component of the nuclear pore complex (NPC) critical for poly(A)+ RNA transport from the nucleus. Related references: PMID:11564755 PMID:11684705
• The protein is encoded by the NUP160 gene (alternative names: KIAA0197, NUP120) and may produce isoforms via alternative splicing.
• NUP160 localizes to the nucleus, specifically to the nuclear pore complex.
• Post-translational modifications include phosphorylation (phosphoprotein keyword), which may regulate its dynamic role in nuclear transport.
• The 'Disease variant' keyword in UniProt indicates its potential link to genetic disorders.
• As part of the NPC, NUP160 participates in protein transport and translocation across the nuclear envelope.

Experimental Guidance and Technical Tips

• The immunogen corresponds to N-terminal residues 40-150 of human NUP160; consider potential cross-reactivity with homologous regions in other species if applicable.
• For Western blot (WB), the predicted molecular weight is approximately 162 kDa; validate band size in the relevant sample system.
• In ELISA assays, coating antigens should be optimized; the fusion protein immunogen may be used as a positive control.
• Human reactivity is expected; reactivity with other species should be verified experimentally.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers one-stop access to IVD raw materials for nuclear transport research, including validated antibodies targeting nucleoporins like NUP160. From monoclonal/polyclonal antibodies to bulk ancillary reagents and rare target sourcing, we support diagnostic manufacturers from concept to clinic. Contact us to explore tailored solutions for your NPC-related assay development.