Anti-NUP155 Rabbit Monoclonal Antibody for WB, ELISA - O75694

Core Product Specifications and Parameters

Biological Background: NUP155 Function and Localization

• NUP155 is a 155 kDa nucleoporin and essential component of the nuclear pore complex (NPC), also referred to as 155 kDa nucleoporin.
• It plays a critical role in nucleocytoplasmic transport by mediating the binding and translocation of proteins across the nuclear envelope.
• NUP155 is implicated in embryogenesis and early development, as it appears essential for proper embryonic growth.
• Subcellularly, NUP155 localizes specifically to the nuclear pore complex and the nuclear membrane.
• The protein is ubiquitously expressed, with detection in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.
• Post‑translational modifications include glycosylation and phosphorylation; disease variants are linked to atrial fibrillation.

Experimental Guidance and Technical Tips

• Given the immunogen region (aa 901–1050), the antibody may target a specific domain; validate in the relevant sample system.
• For Western blot, consider using human or mouse cell lysates expressing NUP155 and confirm a band at ~155 kDa.
• The antibody is listed for WB and ELISA; for other applications (e.g., immunofluorescence), independent validation is recommended.
• Cross‑reactivity with species beyond human and mouse should be tested individually.
• Storage and handling should follow the shipping condition (ice bag) to maintain antibody integrity.

CamelBio: Your One‑Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers and researchers streamlined access to high‑quality IVD raw materials, including validated monoclonal antibodies like this anti‑NUP155 clone. Supporting cell biology and transport research, we provide one‑stop sourcing for optimized antibody pairs, bulk ancillary reagents, and custom development of rare target‑specific materials.