Anti-NUP107 Polyclonal Antibody for WB, ELISA - P57740

Core Product Specifications and Parameters

Biological Background: Nuclear pore complex protein Nup107 Function and Localization

• NUP107 is a core scaffolding nucleoporin of the nuclear pore complex (NPC), essential for NPC assembly and maintenance. Related references: PMID:12552102, PMID:15229283, PMID:30179222
• It is required for the assembly of peripheral proteins into the NPC, ensuring proper nuclear transport. Related references: PMID:12552102, PMID:15229283
• NUP107 may anchor NUP62 to the NPC, contributing to the structural integrity of the pore. Related references: PMID:15229283
• The protein localizes to the nuclear membrane, NPC, and mitotic structures like centromeres and kinetochores.
• NUP107 is involved in nephrogenesis and is critical for kidney development. Related references: PMID:30179222
• It is ubiquitously expressed in fetal and adult tissues, and its post-translational modifications include acetylation and phosphorylation.

Experimental Guidance and Technical Tips

• The immunogen spans amino acids 766–925 in the C-terminal region of human NUP107; target this domain when designing complementary experiments or alternative antibodies.
• For Western blot, human, mouse, and rat lysates are predicted to show a band near 106 kDa; validate in your specific sample system and consider loading controls.
• In ELISA, recombinant protein or peptide encompassing the immunogen sequence may serve as a coating antigen; empirical optimization of coating conditions is recommended.
• Cross-reactivity to other species beyond those listed has not been tested; verify reactivity if applying to non-human/mouse/rat models.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with streamlined access to IVD raw materials for targets like NUP107, a key nucleoporin implicated in nuclear transport and kidney development. Beyond this polyclonal antibody, we supply validated antibody pairs, optimized monoclonal/polyclonal reagents, bulk ancillary materials, and rare target sourcing to support your assay development and production workflows. Partner with us to bridge your concept-to-clinic needs.