Anti-NUDT6 Polyclonal Antibody for WB, IF/ICC, ELISA - P53370

Core Product Specifications and Parameters

Biological Background: NUDT6 Function and Localization

• NUDT6 (Nudix hydrolase 6), also known as GFG, ASFGF2, FGF-AS, and FGF2AS, is a member of the Nudix (nucleoside diphosphate-linked moiety X) hydrolase superfamily.
• Mediates the hydrolysis of some nucleoside diphosphate derivatives, such as NADH and FAD (in vitro) (PubMed:37343711). May contribute to the regulation of cell proliferation (PubMed:11266510). Related references: PMID:37343711 PMID:11266510
• The NUDT6 gene, antisense to FGF2, undergoes alternative splicing, potentially generating multiple isoforms.
• Subcellular localization includes the mitochondrion, nucleus, and cytoplasm.
• Detected at the protein level in liver, kidney, and esophagus, with ubiquitous tissue expression.
• Key functional keywords: Hydrolase, Alternative splicing, Mitochondrion, Nucleus, Cytoplasm.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 121–316 of human NUDT6. For Western blot, expect a band near 36 kDa; consider validating with positive and negative control lysates.
• In immunofluorescence/immunocytochemistry, examine staining patterns consistent with mitochondrial, nuclear, and cytoplasmic localization; use appropriate organelle markers if needed.
• For ELISA, the antibody can potentially be used as a capture or detection reagent after confirmation of performance in the relevant sample matrix and format.
• As a polyclonal antibody, lot-to-lot consistency should be verified by the end user in their specific assay conditions.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers and research laboratories a streamlined pathway to secure high-quality IVD raw materials. Beyond this NUDT6 antibody for nucleotide metabolism and cell proliferation research, we provide validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and sourcing support for difficult-to-find targets. Partner with us to efficiently bridge the gap from discovery to clinical application.