Anti-NAP1L5 Rabbit Polyclonal Antibody for WB and ELISA - Q96NT1

Core Product Specifications and Parameters

Biological Background: NAP1L5 Function and Localization

• Nucleosome assembly protein 1-like 5 (NAP1L5) belongs to the nucleosome assembly protein (NAP) family, a group of histone chaperones that facilitate chromatin assembly and disassembly.
• The protein is also known as histone chaperone NAP1L5 and Down-regulated in liver malignancy (DRLM), reflecting its involvement in chromatin dynamics and potential role in disease.
• Predicted to act as a histone chaperone, NAP1L5 likely participates in DNA replication, transcription, and repair by modulating nucleosome structure.
• Contains a coiled-coil domain, which may mediate protein-protein interactions essential for its chaperone activity.
• Localizes primarily to the nucleus, consistent with its function in chromatin remodeling and gene regulation.
• Predominantly expressed in the brain, suggesting a specialized role in neuronal chromatin organization and neurodevelopment.
• Identified through proteomics and classified as a reference proteome component, supporting its reliability as a research target.

Experimental Guidance and Technical Tips

• For Western blot (WB), expect a single band near 20 kDa corresponding to the predicted molecular weight of NAP1L5.
• Due to the polyclonal nature of the antibody, always include appropriate positive and negative controls to verify specificity in your sample system.
• The antibody is validated for ELISA; consider indirect ELISA for titer determination or antigen quantitation assays.
• Cross-reacts with mouse, making it suitable for studies involving mouse models; validate performance in the specific tissue or cell line of interest.
• Optimal dilution and incubation conditions should be determined empirically; start with standard polyclonal antibody protocols.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic developers and research teams with reliable access to a broad range of IVD raw materials, including this anti-NAP1L5 rabbit polyclonal antibody. For projects in chromatin biology, neuroscience, or cancer research, we offer validated antibody pairs, recombinant proteins, and ancillary reagents to accelerate your workflow. Count on CamelBio to bridge the gap from early-stage discovery to clinical application with streamlined sourcing and expert technical guidance.