Anti-MTERFD3 Rabbit Polyclonal Antibody for WB, ELISA - Q49AM1

Core Product Specifications and Parameters

Biological Background: MTERFD3 Function and Localization

• MTERFD3, also known as mitochondrial transcription termination factor 2 (mTERF2) or mTERF domain-containing protein 3, is encoded by the MTERF2 gene in humans.
• It binds mitochondrial DNA and participates in the regulation of mitochondrial mRNA and rRNA transcription.
• MTERFD3 is a member of the MTERF (mitochondrial transcription termination factor) family, which includes other proteins like MTERF1, MTERF3, and MTERF4, known to regulate mitochondrial gene expression.
• The protein localizes to the mitochondrion, specifically the mitochondrial matrix and nucleoid, where mitochondrial DNA is organized.
• MTERFD3 is expressed in tissues with high energy demands, including skeletal muscle, heart, liver, and pancreas.
• Additional keywords associated with MTERFD3 include transit peptide (indicating mitochondrial targeting), direct protein sequencing, and proteomics identification (based on UniProt annotation).

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal 250 amino acids of human MTERFD3; consider validating detection of both full-length and potential truncated forms in your sample system.
• For Western blotting, a band near 44 kDa is expected; optimize primary antibody dilution and use appropriate molecular weight markers.
• In ELISA, the antibody can be used for direct detection of recombinant MTERFD3 protein or endogenous protein from cell/tissue lysates; ensure proper blocking and washing steps.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers a comprehensive range of IVD raw materials and services, helping you seamlessly advance your diagnostic projects from concept to clinic. Our portfolio for mitochondrial targets like MTERFD3 includes validated polyclonal and monoclonal antibodies, antigen pairs, and ancillary reagents. Contact us to streamline your sourcing, whether you need bulk quantities, custom development, or rare target raw materials.