Anti-MRPS21 Rabbit Polyclonal Antibody for IHC, ELISA - P82921

Core Product Specifications and Parameters

Biological Background: MRPS21 Function and Localization

• MRPS21 encodes the mitochondrial small ribosomal subunit protein bS21m, also referred to as 28S ribosomal protein S21, mitochondrial (MRP-S21 or S21mt).
• It is an integral component of the small (28S) subunit of the mitochondrial ribosome (mitoribosome), which is responsible for translating 13 essential subunits of the oxidative phosphorylation complexes.
• As a ribosomal protein, MRPS21 belongs to the ribosomal protein S21e family and is evolutionarily conserved across eukaryotes.
• Subcellularly, MRPS21 localizes to the mitochondrion, consistent with its role in mitochondrial protein synthesis.
• UniProt keywords indicate that MRPS21 has a known 3D-structure and is identified through proteomic approaches, highlighting its role as a ribonucleoprotein and ribosomal protein.

Experimental Guidance and Technical Tips

• The immunogen used covers the N-terminal region (amino acids 1–87) of human MRPS21; consider epitope conservation when extending to mouse and rat models, as cross-reactivity is reported.
• For immunohistochemistry (IHC-P), standard antigen retrieval methods may be required; optimization of antibody dilution and detection conditions is recommended.
• ELISA is suitable for quantitative detection of MRPS21 protein levels; validate linearity and sensitivity in the relevant sample matrix.
• Always validate the antibody in the specific sample system of interest (e.g., human, mouse, or rat tissues or cells) due to potential species-specific differences.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers and researchers a streamlined, one-stop supply of IVD raw materials, including this anti-MRPS21 rabbit polyclonal antibody for mitochondrial research. Beyond validated antibodies, our inventory encompasses bulk ancillary reagents and rare target sourcing, supporting your transition from concept to clinic. Partner with CamelBio to secure consistent, high-quality materials for your assay development needs.