Anti-MRPS18B Rabbit Polyclonal Antibody for WB, ELISA - Q9Y676

Core Product Specifications and Parameters

Biological Background: MRPS18B Function and Localization

• MRPS18B, also known as Small ribosomal subunit protein mS40, is a mitochondrial ribosomal protein belonging to the small subunit.
• Alternative names include 28S ribosomal protein S18-2, mitochondrial (MRP-S18-2), 28S ribosomal protein S18b, mitochondrial (MRP-S18-b, Mrps18-b, S18mt-b), and Small ribosomal subunit protein bS18b.
• The protein localizes to the mitochondrion, as indicated by its subcellular location and the presence of a transit peptide.
• It is reported as a component of the mitochondrial small ribosomal subunit, suggesting involvement in mitochondrial protein synthesis.
• UniProt keywords classify it as a ribonucleoprotein with a role in mitochondrial translation; additional keywords include 3D-structure, Phosphoprotein, and Proteomics identification.
• The predicted molecular weight is ~29.4 kDa, consistent with the observed band at approximately 29 kDa on Western blots.

Experimental Guidance and Technical Tips

• The immunogen used is a recombinant protein corresponding to full-length human MRPS18B (amino acids 1-258). This design may provide recognition of both native and denatured protein.
• For Western blot (WB), consider optimizing the dilution using a known positive control lysate (e.g., HeLa, HEK293) given the observed molecular weight of ~29 kDa.
• Cross-reactivity with mouse and rat is reported; validate in the relevant sample system before large-scale studies.
• For ELISA applications, the polyclonal nature may enhance signal detection; pair with an appropriate monoclonal detection antibody for sandwich ELISA if required.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop sourcing partner for IVD raw materials, offering a comprehensive portfolio of validated antibodies, bulk ancillary reagents, and custom procurement solutions. This MRPS18B antibody supports research into mitochondrial dysfunction and protein synthesis, and is part of our extensive mitochondrial ribosome target catalog. Whether you need optimized antibody pairs, monoclonal alternatives, or rare target sourcing, CamelBio bridges the gap from concept to clinical application.