Anti-MRPL55 Polyclonal Antibody for WB, ELISA - Q7Z7F7

Core Product Specifications and Parameters

Biological Background: MRPL55 Function and Localization

• MRPL55 encodes the mitochondrial large ribosomal subunit protein mL55 (also known as 39S ribosomal protein L55, L55mt, MRP-L55, and bL31m), a component of the 39S large subunit of the mitochondrial ribosome.
• As a structural constituent of the mitochondrial ribosome, mL55 participates in the translation of 13 essential protein components of the oxidative phosphorylation (OXPHOS) complexes encoded by the mitochondrial genome.
• The protein localizes exclusively to the mitochondria, consistent with its role in the mitochondrial translation machinery.
• MRPL55 is subject to alternative splicing, yielding multiple transcript variants, and is identified as a phosphoprotein in proteomics studies, suggesting potential post-translational regulation.
• Keywords including "Ribonucleoprotein", "Ribosomal protein", and "3D-structure" highlight its integration into the ribonucleoprotein complex and the availability of structural data for this protein.

Experimental Guidance and Technical Tips

• The immunogen used is a recombinant protein corresponding to the N-terminal region (amino acids 1-128) of human MRPL55. Endogenous MRPL55 is predicted to have a molecular weight of ~15 kDa; consider using appropriate gel percentages and transfer conditions for low-molecular-weight proteins in Western blotting.
• For Western blot, recommended starting dilution ranges for polyclonal antibodies are typically 1:500-1:2000, but optimal dilution should be determined empirically using the target cell or tissue lysate.
• This antibody detects human MRPL55; cross-reactivity with other species has not been characterized. Validate in the relevant sample system.
• For ELISA, consider using the recombinant immunogen as a positive control to establish assay conditions.

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CamelBio is your one-stop partner for IVD raw-material sourcing, offering validated antibody pairs, bulk ancillary reagents, and optimized polyclonal antibodies like this anti-MRPL55. With expertise in mitochondrial biology and translational research, we ensure reliable access to rare-target materials and support your diagnostic development from concept to market. Let us bridge your supply needs with quality, consistency, and technical excellence.