Anti-MRPL51 Polyclonal Antibody for WB, ELISA - Q4U2R6

Core Product Specifications and Parameters

Biological Background: MRPL51 Function and Localization

• MRPL51 (Mitochondrial Ribosomal Protein L51), also known as 39S ribosomal protein L51 (L51mt) or bMRP-64, is a core component of the mitochondrial large ribosomal subunit (39S).
• Encoded by the MRPL51 gene, this protein is classified as a ribonucleoprotein essential for mitochondrial translation.
• MRPL51 contains a transit peptide that targets it to the mitochondrion, where it resides within the organelle.
• The protein has been identified through proteomics studies, confirming its expression in human mitochondria.
• Structural data (3D-structure) is available for MRPL51, providing insights into its integration into the mitochondrial ribosome.
• The theoretical molecular weight of MRPL51 is approximately 15.1 kDa (15095 Da), consistent with its designation as a small ribosomal protein.

Experimental Guidance and Technical Tips

• This polyclonal antibody was generated against a recombinant fusion protein spanning amino acids 1-128 of human MRPL51. It is predicted to detect the full-length ~15 kDa protein in Western blotting.
• Cross-reactivity with mouse and rat MRPL51 enables multi-species studies; however, sequence alignment is recommended to confirm epitope conservation.
• For Western blot, consider loading adequate amounts of mitochondrial-enriched protein lysate to ensure detection, given MRPL51's mitochondrial localization.
• Validate antibody performance in your specific sample type, as endogenous expression levels may vary across tissues and cell lines.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop partner for IVD raw material sourcing, offering validated antibody pairs, bulk polyclonal and monoclonal antibodies, and ancillary reagents for mitochondrial research. For projects targeting mitochondrial ribosomal proteins such as MRPL51, CamelBio provides integrated access to rare-target raw materials, technical services, and consulting support—from initial concept through to clinical application.