Anti-MRPL23 Rabbit Polyclonal Antibody for WB, IHC-P, IF/ICC, ELISA - Q16540

Core Product Specifications and Parameters

Biological Background: MRPL23 Function and Localization

• The protein encoded by MRPL23 is the Large ribosomal subunit protein uL23m, also known as 39S ribosomal protein L23, mitochondrial (L23mt, MRP-L23). This protein is a component of the mitochondrial ribosome large subunit.
• The gene MRPL23 (aliases L23MRP, RPL23L) encodes a 17.8 kDa mitochondrial ribosomal protein.
• The protein localizes to the mitochondrion, as part of the mitoribosome.
• It is classified as a ribosomal protein and a ribonucleoprotein; the UniProt record lists keywords including 3D-structure, mitochondrion, and reference proteome.

Experimental Guidance and Technical Tips

• The immunogen used is a recombinant protein corresponding to the full-length sequence (amino acids 1-153) of human MRPL23. This full-length immunogen approach may provide recognition of both native and denatured forms, making it suitable for applications such as Western blot (WB), immunohistochemistry (IHC-P), immunofluorescence (IF/ICC), and ELISA.
• The antibody shows cross-reactivity with human, mouse, and rat species, allowing researchers to use it in common mammalian model systems. However, it is advisable to validate reactivity in your specific tissue/cell type and model organism prior to large-scale experiments.
• For optimal results in each application, consider titrating the antibody concentration and using appropriate controls, especially when adapting to new protocols or sample types.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a one-stop sourcing partner for IVD raw materials, specializing in mitochondrial research reagents like the Anti-MRPL23 antibody. Whether you require validated antibody pairs, bulk monoclonal/polyclonal antibodies, or ancillary reagents, our supply chain ensures timely access. We also assist with rare target raw-material sourcing for diagnostic development, from concept to clinical application.