Anti-MRPL13 Polyclonal Antibody for WB, IHC-P, ELISA - Q9BYD1

Core Product Specifications and Parameters

Biological Background: MRPL13 Function and Localization

• MRPL13 is the mitochondrial 39S ribosomal protein L13, a component of the large subunit of the mitochondrial ribosome.
• As a ribosomal protein, it is predicted to participate in mitochondrial protein synthesis, essential for organelle function.
• The protein is localized exclusively to mitochondria, consistent with its role in the mitochondrial translation machinery.
• Post-translational modifications include acetylation, which may modulate ribosome assembly or stability.
• Structural studies (3D-structure keyword) have contributed to understanding the architecture of the mitochondrial ribosome.
• Aliases include L13mt, MRP-L13, L13A, and RPML13; it belongs to the universal ribosomal protein uL13 family.
• Keywords such as ribonucleoprotein, ribosomal protein, and reference proteome underscore its conserved and fundamental role.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (aa 1-178); validate the expected band size of ~21 kDa in Western blotting.
• For immunohistochemistry (IHC-P), consider antigen retrieval optimization and co-staining with mitochondrial markers like COX IV.
• Verify species cross-reactivity in your own experimental system; the antibody has been shown to recognize human, mouse, and rat MRPL13.
• Include appropriate loading controls and test multiple tissue or cell lysates to confirm specificity.
• As a polyclonal antibody, lot-to-lot consistency may vary; perform initial titration and maintain a single lot for comparative studies.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. This anti-MRPL13 polyclonal antibody is part of our extensive catalog supporting mitochondrial research and assay development. Whether you need validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, or rare target raw-material sourcing, CamelBio ensures reliable supply to streamline your workflow.