Anti-MPC2 Polyclonal Antibody for WB, IHC-P, ELISA - O95563

Core Product Specifications and Parameters

Biological Background: MPC2 Function and Localization

• Mediates the uptake of pyruvate into mitochondria to maintain the balance between glycolysis and oxidative phosphorylation. Related references: PMID:22628558, PMID:26253029, PMID:27317664
• Plays an essential role in cellular metabolism. Related references: PMID:40044865, PMID:40101766
• Localizes to the mitochondrion inner membrane.
• Also known as Brain protein 44 (BRP44) and Solute carrier family 54 member 2 (SLC54A2).
• Belongs to the mitochondrial pyruvate carrier family and functions as a transporter.
• Contains transmembrane helices and is annotated with keywords: 3D-structure, Membrane, Mitochondrion, Mitochondrion inner membrane, Proteomics identification, Reference proteome, Transmembrane, Transmembrane helix, Transport.

Experimental Guidance and Technical Tips

• The immunogen is a synthetic peptide from the N-terminal region (aa 1-60), which may be suitable for detecting MPC2 in western blotting (WB) and immunohistochemistry (IHC-P).
• Expected protein weight is approximately 14 kDa; consider using appropriate gel percentage and transfer conditions.
• Cross-reactivity with mouse and rat suggests potential use in these species; validate in the relevant sample system.
• For ELISA applications, confirm optimal coating conditions and antibody dilutions experimentally.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers and research labs with one-stop access to IVD raw materials, technical services, and consulting. For mitochondrial metabolism research, we offer optimized MPC2 antibodies and can source validated antibody pairs, bulk ancillary reagents, and rare‑target raw materials to streamline your project from concept to clinic.