Anti-Mouse CD138/Syndecan-1 Monoclonal Antibody () for Flow Cytometry - P18828

Core Product Specifications and Parameters

Biological Background: CD138/Syndecan-1 Function and Localization

• Syndecan-1 is a cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate chains, and it links the cytoskeleton to the interstitial matrix.
  Related references: PMID:8163535
• It regulates exosome biogenesis in concert with SDCBP and PDCD6IP.
• Syndecan-1 can induce its own expression in dental mesenchymal cells and in neighboring dental epithelial cells via an MSX1-mediated pathway.
  Related references: PMID:8898217
• Subcellular localization includes the plasma membrane, secreted forms, and extracellular exosomes.
• It undergoes alternative splicing, generating multiple isoforms, and is post-translationally modified with heparan sulfate, phosphorylation, and glycosylation.
• The protein functions as a key component of the extracellular matrix, influencing cell adhesion, migration, and signaling.

Experimental Guidance and Technical Tips

• The immunogen used corresponds to the extracellular domain (amino acids 23–255) of mouse CD138/Syndecan-1, making this antibody suitable for detection of the surface‑exposed epitope in flow cytometry.
• Since the antibody is directly conjugated to , protect it from light and minimize repeated freeze‑thaw cycles to maintain fluorescence intensity.
• For flow cytometry, titrate the antibody to determine the optimal working dilution for your specific cell type; commonly, CD138 is expressed on plasma cells, myeloma cells, and some epithelial cells.
• Include appropriate isotype controls and validate the staining pattern in your sample system to confirm specificity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with one‑stop access to IVD raw materials, technical services, and consulting — covering every stage from concept to clinic. For CD138/Syndecan-1 research and assay development, we supply validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and specialized rare‑target raw‑material sourcing. Partner with CamelBio to streamline your procurement, ensure supply chain continuity, and accelerate your project timelines.