anti-Mouse CD11c Monoclonal Antibody for FC - Q9QXH4

Core Product Specifications and Parameters

Biological Background: Integrin alpha-X Function and Localization

• Integrin alpha-X (CD11c) is the alpha subunit of the integrin alpha-X/beta-2 complex, also known as leukocyte adhesion glycoprotein p150,95.
• It functions as a receptor for fibrinogen, recognizing the G-P-R sequence, and mediates cell-cell interaction during inflammatory responses.
• This integrin is especially important in monocyte adhesion and chemotaxis, playing a critical role in immune cell trafficking.
• Integrin alpha-X serves as a receptor for the erythrocyte-specific adhesion molecule ICAM4, mediating erythrophagocytosis.
• The protein is localized to the cell membrane, consistent with its role in cell adhesion and signaling.
• It features calcium and magnesium binding sites, disulfide bonds, and extensive glycosylation, reflecting its functional requirements.
• With a molecular weight of approximately 129 kDa, it belongs to the integrin family and contains typical structural repeats and transmembrane helices.

Experimental Guidance and Technical Tips

• The immunogen was generated using a recombinant protein of mouse CD11c; thus, the antibody may recognize a conformational epitope—consider optimizing staining conditions for flow cytometry.
• As the antibody is validated for Flow Cytometry (FC), perform appropriate titration and include necessary controls to ensure high signal-to-noise ratios in your experiments.
• CD11c is predominantly expressed on dendritic cells and some monocyte/macrophage populations; validate the antibody in relevant mouse immune cell samples to confirm specificity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a one-stop sourcing partner for IVD raw materials, offering validated antibodies such as this anti-Mouse CD11c monoclonal antibody to support your immunology and cell adhesion research. We provide optimized antibody pairs, bulk ancillary reagents, and rare‑target sourcing to streamline your flow cytometry workflows. From concept to clinic, CamelBio connects you with trusted supplies and technical expertise, accelerating your diagnostic and research development.