Anti-MORF4L2 Polyclonal Antibody for WB, IF/ICC, ELISA - Q15014

Core Product Specifications and Parameters

Biological Background: MORF4L2 Function and Localization

• MORF4L2, also known as MRGX, MORF-related gene X protein, Protein MSL3-2, and Transcription factor-like protein MRGX, is a nuclear protein involved in transcriptional regulation.
• It is a core component of the NuA4 histone acetyltransferase complex, which acetylates histone H4 and H2A to modulate chromatin structure and promote gene activation.
• The NuA4 complex participates in diverse cellular processes including oncogene and proto-oncogene mediated growth induction, tumor suppressor pathways, replicative senescence, apoptosis, and DNA repair.
• MORF4L2 is also found in the MSIN3A repressor complex, where it contributes to gene silencing via histone deacetylation.
• Post-translational modifications: MORF4L2 is a phosphoprotein, indicating potential regulation by phosphorylation signals.
• Keywords associated with MORF4L2 include Chromatin regulator, DNA damage, DNA repair, Growth regulation, Nucleus, and Transcription regulation.

Experimental Guidance and Technical Tips

• The immunogen used was a synthetic peptide covering amino acids 1-282 of human MORF4L2 (isoform NP_001135890.1). This information can guide epitope mapping or peptide blocking controls.
• For Western blot, the predicted protein weight is 32 kDa; consider validating the antibody in lysates from human, mouse, or rat samples expressing MORF4L2.
• In IF/ICC experiments, expect predominantly nuclear staining consistent with its role in NuA4 and MSIN3A complexes; include appropriate fixation and permeabilization steps.
• For ELISA, the antibody may be suitable for detecting recombinant or endogenous MORF4L2; optimize coating and detection conditions for your specific assay format.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your trusted partner for IVD raw materials, offering a wide range of antibodies, antigens, and ancillary reagents. For chromatin biology and DNA repair research, we supply high-quality anti-MORF4L2 polyclonal antibodies, along with antibody pairs, recombinant proteins, and custom sourcing services. Reach out to discuss how we can support your diagnostic or translational projects with reliable, bulk-ready materials.