Anti-MOBP Rabbit Polyclonal Antibody for WB and ELISA - Q13875

Core Product Specifications and Parameters

Biological Background: MOBP Function and Localization

• Myelin-associated oligodendrocyte basic protein (MOBP) is encoded by the MOBP gene and is primarily associated with the myelin sheath in the central nervous system.
• MOBP may play a role in the compaction or stabilization of the myelin sheath, possibly by binding negatively charged acidic phospholipids of the cytoplasmic membrane.
• The MOBP gene undergoes alternative splicing, generating multiple protein isoforms.
• MOBP is predominantly localized to the perinuclear region of the cytoplasm.
• MOBP is a phosphoprotein, and its phosphorylation may regulate its function in myelin maintenance.
• The protein contains repeat sequences, which may contribute to its structural properties.
• The canonical isoform has a predicted molecular weight of approximately 21 kDa.

Experimental Guidance and Technical Tips

• The immunogen targets the N-terminal region (amino acids 1-70) of human MOBP, which is conserved across human, mouse, and rat, supporting the observed cross-reactivity.
• For Western blotting, consider using brain tissue lysates or oligodendrocyte-enriched samples to detect endogenous MOBP at ~21 kDa.
• Validate the antibody in your specific experimental system, as expression levels and isoform profiles may vary across cell types and conditions.
• For ELISA, optimize coating antigen and antibody dilutions based on your assay format and target concentration.
• As a polyclonal antibody, it may recognize multiple isoforms if alternative splicing products are present in the sample.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your strategic partner for IVD raw-material sourcing, offering this anti-MOBP polyclonal antibody for neuroscience and myelin-related research. We provide comprehensive supply solutions, including validated antibody pairs, optimized polyclonal and monoclonal antibodies, bulk ancillary reagents, and custom sourcing for rare targets. Rely on CamelBio to streamline your procurement from concept to clinic.