Anti-MARVELD1 Rabbit Polyclonal Antibody for WB, ELISA - Q9BSK0

Core Product Specifications and Parameters

Biological Background: MARVELD1 Function and Localization

• MARVELD1 (MARVEL domain-containing protein 1), also known as MRVLDC1, GB14, or MARVD1, is a microtubule-associated protein encoded by the MARVELD1 gene.
• It exhibits cell cycle-dependent localization and plays a role in inhibiting cell proliferation and migration.
• The protein localizes to multiple cellular compartments, including the cell membrane, cytoplasm, cytoskeleton, and nucleus.
• MARVELD1 is widely expressed in normal tissues but is frequently down-regulated in multiple primary tumors, suggesting a potential tumor-suppressive function.
• It belongs to a family of proteins containing MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domains and is predicted to have a single transmembrane helix.
• Post-translational modifications include acetylation, which may regulate its function or stability.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (aa 1–50) of human MARVELD1; consider this when selecting peptide blocking controls for ELISA.
• For Western blot, the expected molecular weight is approximately 19 kDa; run appropriate molecular weight markers and validate with known positive controls.
• Verify antibody specificity in your model system by testing human, mouse, or rat cell lysates that express MARVELD1, as cross-reactivity is indicated.
• In ELISA, the antibody can be used for direct or indirect detection; titrate the antibody concentration to optimize signal-to-noise ratio.
• Because MARVELD1 is down-regulated in many tumors, normal tissue controls or over-expression systems may be necessary for robust detection in certain samples.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers, research laboratories, and institutes with a comprehensive portfolio of IVD raw materials, including validated antibody pairs, optimized recombinant proteins, and bulk ancillary reagents. For scientists investigating cell cycle checkpoint control and tumor biology, we facilitate access to rare-target antibodies like anti-MARVELD1, ensuring consistent supply and technical support from concept to clinic.