Anti-LYZL6 Polyclonal Antibody for WB and ELISA - O75951

Core Product Specifications and Parameters

Biological Background: Lysozyme-like protein 6 (LYZL6) Function and Localization

• LYZL6 is a member of the lysozyme-like protein family, with a mature molecular weight of approximately 17 kDa (UniProt: 16956 Da).
• It exhibits pH-dependent bacteriolytic activity, with optimal activity around pH 5.6, and shows activity against Gram-positive bacteria including Micrococcus luteus and Staphylococcus aureus. Related references: PMID:24013621 PMID:28182716
• LYZL6 may play a role in fertilization by mediating sperm-egg plasma membrane adhesion and fusion. Related references: PMID:28182716
• The protein is secreted and localizes to the cell surface, specifically on cilia and flagella of spermatozoa.
• LYZL6 contains potential disulfide bonds, characteristic of lysozyme family proteins, which may stabilize its structure.
• It is primarily expressed in testis, epididymis, and spermatozoa, with specific expression in late-stage spermatocytes and round spermatids. Related references: PMID:16014814 PMID:28182716
• As a glycosidase and hydrolase, LYZL6 functions as an antimicrobial enzyme, contributing to innate immunity in the male reproductive tract.

Experimental Guidance and Technical Tips

• The immunogen spans amino acids 20–148, covering nearly the full-length mature LYZL6 protein. For Western blot, a band of approximately 17 kDa is expected in reducing conditions; validate using human testis or epididymis tissue lysates.
• In ELISA applications, consider optimizing the coating antigen concentration and antibody dilution for your specific assay format. Since cross-reactivity is limited to human, this antibody is suitable for detecting human LYZL6 in biological samples.
• For immunofluorescence or other applications not listed, pilot experiments are recommended to confirm performance.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with a comprehensive portfolio of IVD raw materials, including this anti-LYZL6 polyclonal antibody for fertility and antimicrobial research. We supply validated antibody pairs, optimized monoclonal/polyclonal antibodies, and bulk ancillary reagents to streamline your assay development. For rare target raw-material sourcing, our one-stop service covers every stage from concept to clinic, ensuring reliable access to high-quality reagents.