Anti-Lysozyme (LYZ) Rabbit Monoclonal Antibody for WB, IF-P, ELISA - P61626

Core Product Specifications and Parameters

Biological Background: Lysozyme (LYZ) Function and Localization

• Lysozyme C (LYZ) is a 16.5 kDa secreted antimicrobial enzyme encoded by the LYZ gene (SWISS: P61626).
• Functions primarily as a 1,4-beta-N-acetylmuramidase, catalyzing the hydrolysis of peptidoglycan to induce bacterial cell lysis.
• Associated with the monocyte-macrophage system in tissues and body fluids, enhancing immunoagent activity.
• Secreted into extracellular spaces, including blood, tears, and mucosal surfaces, contributing to innate immune defense.
• Belongs to the glycosyl hydrolase 22 family and contains structurally essential disulfide bonds.
• Implicated in hereditary systemic amyloidosis; certain mutations in LYZ are linked to disease variants.
• Identified as a reference proteomic component with potential as a biomarker (manual annotation evidence).

Experimental Guidance and Technical Tips

• The immunogen encompasses the N-terminal region (aa 1-100) of human Lysozyme C, a segment conserved across species; verify sequence alignment when using non-human samples.
• For Western blotting, a band at approximately 17 kDa is typically observed under reducing conditions; consider including a positive control such as human serum or tissue lysate.
• In ELISA and IF-P applications, empirically determine optimal antibody dilutions and validate in the relevant biological sample system.
• Given the secreted nature of LYZ, ensure sample preparation includes secreted fractions or adequate tissue perfusion.

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As a dedicated one-stop sourcing platform for IVD raw materials, CamelBio supports diagnostic developers and research teams with reliable access to critical reagents like this anti-Lysozyme (LYZ) antibody. Whether you need validated antibody pairs, bulk monoclonal antibodies, or rare target sourcing for innate immunity and infectious disease assays, we streamline procurement from concept to clinic. Let CamelBio serve as your bridge to quality raw materials and technical support.