Anti-LUC7L2 Polyclonal Antibody for WB, ELISA - Q9Y383

Core Product Specifications and Parameters

Biological Background: LUC7L2 Function and Localization

• LUC7L2 (Putative RNA-binding protein Luc7-like 2) is a member of the Luc7-like protein family, also known by aliases CGI-59, CGI-74, or LUC7B2.
• The protein contains an Arg/Ser-rich domain, which is characteristic of RNA-binding proteins and suggests a potential role in pre-mRNA splicing regulation.
• It localizes predominantly to nuclear speckles and the nucleoplasm, subnuclear compartments closely associated with mRNA processing and splicing factor storage.
• Post-translational modifications such as phosphorylation and hydroxylation have been identified, which may modulate its function or interactions within the spliceosome.
• Keywords including alternative splicing, coiled coil, and proteomics identification highlight its involvement in splicing-related processes and its detection in mass spectrometry studies.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 313–392 of human LUC7L2, a region likely within the Arg/Ser-rich domain; consider potential epitope accessibility when optimizing detection conditions.
• For Western blot, the predicted band size is approximately 47 kDa, but post-translational modifications may cause slight shifts; validate with appropriate positive and negative controls.
• Cross-reactivity with mouse is reported; confirm reactivity in your specific mouse strain or tissue and consider performing an alignment check if using other species.
• ELISA can be employed for quantitative or screening purposes; optimize coating antigen and antibody dilution under standard laboratory protocols.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic developers and research teams a streamlined source for high-quality IVD raw materials, including this LUC7L2 polyclonal antibody. From validated antibody reagents to bulk ancillary supplies and rare target sourcing, we bridge the gap between discovery and assay development. Let us support your splicing and gene expression research with reliable, application-tested products and flexible procurement solutions.