Anti-LSP1 Rabbit Monoclonal Antibody for WB, IF/ICC, IF-P, ELISA - P33241

Core Product Specifications and Parameters

Biological Background: LSP1 Function and Localization

• LSP1 (Lymphocyte-specific protein 1) is also known as 47 kDa actin-binding protein, 52 kDa phosphoprotein (pp52), and lymphocyte-specific antigen WP34.
• LSP1 may play a role in mediating neutrophil activation and chemotaxis.
• LSP1 localizes to the cell membrane.
• It is specifically expressed in activated T-lymphocytes.
• The protein undergoes post-translational modifications including acetylation and phosphorylation.
• Alternative splicing generates multiple isoforms of LSP1.
• The UniProt-curated molecular weight is 37192 Da (approximately 37 kDa), and LSP1 is classified as a reference proteome member.

Experimental Guidance and Technical Tips

• The immunogen design covers amino acids 240–339, which may contribute to specificity; consider sequence alignment with relevant isoforms and orthologs for cross-reactivity assessment.
• For Western blot, a specific band around 37 kDa is expected; validate detection in appropriate positive controls such as activated T-lymphocyte lysates.
• In immunofluorescence applications (IF/ICC, IF-P), membrane localization should be observed; co-staining with a known membrane marker can aid confirmation.
• For ELISA, the antibody may serve as a capture or detection reagent; optimize coating, blocking, and detection conditions for your specific assay format.
• Include species-appropriate controls (human, mouse, rat) to confirm cross-reactivity as indicated.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research institutes with streamlined access to high-quality IVD raw materials. This LSP1 monoclonal antibody supports immunological research into neutrophil biology and adaptive immunity. Beyond single reagents, we supply validated antibody pairs, optimized bulk monoclonal and polyclonal antibodies, ancillary reagents, and rare target sourcing—helping you progress from concept to clinic with a single, reliable partner.