Anti-LPP Monoclonal Antibody for WB, IHC-P, IF/ICC, ELISA - Q93052

Core Product Specifications and Parameters

Biological Background: LPP Function and Localization

• Lipoma-preferred partner (LPP) is also known as LIM domain-containing preferred translocation partner in lipoma, encoded by the LPP gene (Gene ID: 4026).
• LPP plays a structural role at sites of cell adhesion, contributing to the maintenance of cell shape and motility, and may also function in signal transduction from cell adhesion sites to the nucleus.
• Proposed to serve as a scaffold protein facilitating the assembly of distinct protein complexes in both the cytoplasm and the nucleus, integrating signals from soluble factors and cell-cell adhesion.
• Subcellular localization includes the nucleus, cytoplasm, cell junction, and cell membrane, consistent with its dual roles in structural support and signaling.
• Post-translational modifications include acetylation, phosphorylation, and isopeptide bond formation, as indicated by keyword annotations.
• Contains LIM domains and zinc-binding motifs, classifying it as a metal-binding protein with potential regulatory functions.
• Tissue expression is broad, with notably low or absent expression in brain and peripheral leukocytes.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (amino acids 1-100) of human LPP, which may confer target specificity; consider verifying the epitope recognition in your assay.
• For Western blot (WB), the expected molecular weight is approximately 66 kDa; use appropriate molecular weight markers and validate band size in relevant cell or tissue lysates.
• For immunohistochemistry (IHC-P) and immunofluorescence (IF/ICC), optimize antigen retrieval and permeabilization conditions, and include appropriate controls.
• This antibody is reported to cross-react with human and mouse samples; confirm reactivity with your specific experimental system.
• For ELISA, the antibody can be evaluated as either capture or detection reagent; consider paired screening if building a sandwich assay.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your trusted one-stop partner for IVD raw-material sourcing, offering validated monoclonal antibodies, optimized antibody pairs, and bulk ancillary reagents for diagnostic development. This anti-LPP antibody supports research into cell adhesion, cytoskeletal dynamics, and cancer biology, with applications spanning WB, IHC-P, IF/ICC, and ELISA. Whether you need rare target raw materials or scalable supply solutions, CamelBio bridges your concept to clinic with comprehensive technical and procurement support.