Anti-LBP Polyclonal Antibody for WB, IF/ICC, ELISA - P18428

Core Product Specifications and Parameters

Biological Background: LBP Function and Localization

• Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Related references: PMID:24120359 PMID:7517398
• Acts as an affinity enhancer for CD14, facilitating its association with LPS.
• Promotes the release of cytokines in response to bacterial lipopolysaccharide. Related references: PMID:24120359 PMID:7517398
• Subcellular localization: Secreted protein, also associated with cytoplasmic granule membrane.
• Detected in blood serum at the protein level.
• Exhibits antibiotic and antimicrobial properties; functions in innate immunity and lipid transport.

Experimental Guidance and Technical Tips

• As a polyclonal antibody generated against a synthetic peptide (aa 250-350), it is expected to recognize multiple linear epitopes on LBP.
• Recommended applications include Western blotting (WB), immunofluorescence/immunocytochemistry (IF/ICC), and ELISA.
• Cross-reactivity with mouse and rat LBP allows versatility across species models; however, validation in the specific sample system is advised.
• For WB, consider loading appropriate positive controls (e.g., serum samples or LPS-stimulated cells) and verify the band at the predicted molecular weight (53 kDa).
• Optimal dilutions and incubation conditions should be experimentally determined.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is dedicated to equipping diagnostic manufacturers and research labs with a comprehensive range of IVD raw materials, including this anti-LBP antibody for innate immunity and infectious disease applications. Beyond single reagents, we supply validated antibody pairs, optimized polyclonal and monoclonal antibodies, bulk ancillary reagents, and specialized raw-material sourcing for rare targets. Partner with CamelBio to streamline your journey from initial concept to clinical application.