Anti-LARP1B Polyclonal Antibody for WB, IHC-P, ELISA - Q659C4

Core Product Specifications and Parameters

Biological Background: LARP1B Function and Localization

• LARP1B (La-related protein 1B) is annotated as an RNA-binding protein in UniProt, suggesting a role in RNA metabolism or stability.
• It is a member of the La-related protein (LARP) family, also referred to as La ribonucleoprotein domain family member 1B or LARP2.
• The LARP1B gene undergoes alternative splicing, potentially producing multiple protein isoforms.
• The protein is classified as a phosphoprotein, indicating that its activity or interactions may be regulated by phosphorylation.
• LARP1B has been identified in large-scale proteomic studies, confirming its expression at the protein level.
• It is part of the UniProt reference proteome for Homo sapiens, reflecting well-annotated experimental evidence.
• The predicted molecular mass of the canonical isoform is approximately 105 kDa.

Experimental Guidance and Technical Tips

• The immunogen for this antibody covers amino acids 170–320 of human LARP1B; this region appears conserved across human, mouse, and rat based on reported cross-reactivity.
• For western blot analysis, the expected band size is ~105 kDa; consider using a 7.5% or 8% SDS-PAGE gel and optimize transfer time according to your system.
• In immunohistochemistry (IHC-P), validation of the antibody dilution and antigen retrieval method in the relevant tissue type is recommended.
• When used in ELISA, include both positive and negative controls to ensure signal specificity and assay linearity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a comprehensive supplier of IVD raw materials, offering validated antibodies, bulk reagents, and custom sourcing services for diagnostic and research applications. The anti-LARP1B polyclonal antibody is part of our portfolio for studying RNA-binding proteins, supporting projects from target identification to assay development. Our team can assist with technical consultation and procurement of rare-target materials to accelerate your workflow.