Anti-LAMP3 Rabbit Polyclonal Antibody for WB, IHC-P, ELISA - Q9UQV4

Core Product Specifications and Parameters

Biological Background: LAMP3 Function and Localization

• LAMP3 is a lysosome-associated membrane glycoprotein belonging to the LAMP family, also known as CD208 or DC-LAMP.
• It participates in the unfolded protein response (UPR), aiding protein degradation and promoting cell survival under proteasomal stress. Related references: PMID:25681212
• LAMP3 modulates autophagy by facilitating the fusion of lysosomes with autophagosomes. Related references: PMID:24434718
• It promotes hepatocellular lipogenesis via activation of the PI3K/Akt signaling pathway. Related references: PMID:29056532
• LAMP3 may contribute to dendritic cell maturation and adaptive immune responses. Related references: PMID:9768752
• The protein localizes to the lysosome, endosomes, cytoplasmic vesicles, and the cell surface.
• It is expressed in lymphoid tissues, dendritic cells, lung, and is upregulated in various carcinomas.
• LAMP3 plays roles in microbial infection, including supporting influenza A virus replication, mumps virus fusion protein processing, and Salmonella typhimurium proliferation.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 140–380 of human LAMP3, which may detect full‑length LAMP3 and potential isoforms; consider validating band patterns in your specific sample system.
• For Western blotting, note the predicted molecular weight of 44 kDa; glycosylation and other modifications may cause a higher apparent molecular weight. Confirm with appropriate positive control lysates from human, mouse, or rat tissues.
• In IHC‑P, optimize antigen retrieval and antibody titration; ensure proper fixation and permeabilization for reliable staining.
• For ELISA, the antibody can be used as a capture or detection reagent; pair with validated antigen standards and optimize assay conditions.
• Cross‑reactivity with human, mouse, and rat suggests conserved epitope recognition; verify performance in your target species.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one‑stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. Our LAMP3 polyclonal antibody is part of a comprehensive portfolio for autophagy, dendritic cell biology, and infectious disease research. Beyond this product, we offer validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target raw‑material sourcing to accelerate your assay development and manufacturing.