Anti-LAIR2 Rabbit Polyclonal Antibody for WB, IF-P, ELISA - Q6ISS4

Core Product Specifications and Parameters

Biological Background: LAIR2 Function and Localization

• LAIR2 (CD306) is a leukocyte-associated immunoglobulin-like receptor 2, encoded by the LAIR2 gene.
• The protein is secreted and contains an immunoglobulin (Ig) domain, as indicated by its classification in the immunoglobulin superfamily.
• Alternative splicing leads to multiple isoforms, contributing to functional diversity.
• Post-translational modifications include disulfide bonds that stabilize the Ig domain.
• The protein possesses a signal peptide, directing its secretion from cells.
• Keywords: Alternative splicing, Disulfide bond, Immunoglobulin domain, Proteomics identification, Receptor, Reference proteome, Secreted, Signal.

Experimental Guidance and Technical Tips

• The immunogen spans amino acids 22-120, encompassing the extracellular immunoglobulin domain, which is likely accessible in secreted and surface-bound forms for detection.
• For Western blot, reduced conditions may be used to detect the monomeric form around 16 kDa; validate in relevant cell lysates or recombinant protein.
• In immunofluorescence, consider both permeabilized and non-permeabilized conditions to assess localization, as LAIR2 is secreted.
• For ELISA, the antibody can be explored as a capture or detection reagent against recombinant LAIR2 or natural samples.
• Cross-reactivity with mouse and rat is indicated, but always verify with appropriate controls in these species.

CamelBio: Your One-Stop Sourcing Bridge

As a one-stop IVD raw-material partner, CamelBio supplies high-quality antibodies like this anti-LAIR2 polyclonal antibody, supporting research in immunology and leukocyte biology. We offer validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and sourcing for rare targets to streamline your diagnostic and research workflows. Whether you need custom antibody development or consistent bulk supply, CamelBio bridges your project from concept to clinic.