Anti-KRBOX4 Polyclonal Antibody for WB, ELISA - Q5JUW0

Core Product Specifications and Parameters

Biological Background: KRBOX4 Function and Localization

• KRBOX4 (KRAB domain-containing protein 4), also known as ZNF673 or KRABD4, is encoded by the KRABD4 gene in humans.
• It belongs to the KRAB (Krüppel-associated box) domain-containing protein family, a motif often involved in protein-protein interactions and transcriptional modulation.
• According to UniProt, KRBOX4 is expressed in a broad range of tissues, including brain, ovary, testis, prostate, tonsil, heart, bone marrow, colon, breast, and kidney.
• The gene exhibits alternative splicing, and the protein is included in the reference proteome set; it has been identified by proteomics identification approaches.
• The predicted molecular weight is approximately 20 kDa.

Experimental Guidance and Technical Tips

• The immunogen is a synthetic peptide derived from the region spanning amino acids 100 to the C-terminus of human KRBOX4; for Western blot, the expected band is around 20 kDa. Validate detection in lysates from human, mouse, and rat tissues.
• For ELISA, consider indirect or sandwich ELISA formats using the peptide antigen or recombinant KRBOX4 protein. Optimize coating and antibody concentrations.
• Since KRBOX4 expression is widespread, check relevant tissue or cell line samples for positive controls; avoid tissue types listed as negative in your experimental system.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a one-stop partner for IVD raw material sourcing, supporting diagnostic manufacturers and research labs with validated antibodies, bulk reagents, and technical services. For targets like KRBOX4 and related nuclear proteins, we supply optimized polyclonal and monoclonal antibodies, antibody pairs, and ancillary reagents to accelerate kit development and translational research. Let CamelBio bridge your requirements from discovery to clinical application.