Anti-ITIH4 Rabbit Polyclonal Antibody for WB, ELISA - Q14624

Core Product Specifications and Parameters

Biological Background: ITIH4 Function and Localization

• ITIH4 (Inter-alpha-trypsin inhibitor heavy chain H4) is a member of the inter-alpha-trypsin inhibitor (ITI) family, also known as inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP) or plasma kallikrein-sensitive glycoprotein 120 (PK-120).
• It functions as a type II acute-phase protein (APP), playing a role in inflammatory responses to trauma and liver development or regeneration.
• ITIH4 is a secreted glycoprotein with liver-specific expression, characterized by alternative splicing, disulfide bonds, and a serine protease inhibitor domain.
• The protein's molecular weight is approximately 103 kDa, and it has been structurally characterized, with 3D-structure data available.

Experimental Guidance and Technical Tips

• The immunogen was a recombinant fusion protein covering amino acids 689-930 of human ITIH4; consider using this region for validation or epitope mapping.
• This polyclonal antibody is suitable for Western blot (WB) and ELISA applications; optimize dilution factors and detection conditions for your specific experimental setup.
• Cross-reactivity is confirmed for human ITIH4; for other species, verify experimentally if required.
• In WB, a band at ~103 kDa is expected; ensure appropriate gel composition and transfer parameters.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. For research involving ITIH4 and acute-phase inflammatory responses, we offer validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and rare target raw-material sourcing to accelerate your diagnostic development. Partner with CamelBio to streamline your project from discovery to commercialization.