Anti-Human CD7 Monoclonal Antibody for Flow Cytometry (FC) - P09564

Core Product Specifications and Parameters

Biological Background: CD7 Function and Localization

• CD7, also known as GP40, TP41, Tp40, or LEU-9, is a T-cell antigen encoded by the CD7 gene.
• It is a transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Related references: PMID:7506726
• CD7 plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. Related references: PMID:10652336
• This interaction mediates the production of cytokines such as IL-2. Related references: PMID:1709867
• On resting NK cells, CD7 activation results in a significant induction of interferon-gamma levels. Related references: PMID:7506726
• Subcellular localization is at the membrane.
• Keywords associated with CD7 include adaptive immunity, immunoglobulin domain, disulfide bond, glycoprotein, lipoprotein, palmitate, receptor, and transmembrane helix.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the extracellular region (amino acids 26-180), which is expected to be accessible on native membrane CD7; consider this for flow cytometry (FC) applications on live, unfixed cells.
• This rabbit monoclonal antibody may be suited for FC detection of human CD7 on T-cells and NK cells; validate in the relevant sample system using appropriate isotype controls and compensation settings.
• If additional detection steps are needed (e.g., indirect staining), use a suitable anti-rabbit IgG secondary antibody conjugated to a compatible fluorophore.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, including validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target raw-material sourcing for targets such as CD7. This rabbit anti-human CD7 monoclonal antibody is part of our broad portfolio for immunology and immune cell profiling applications. Whether you need small-scale research aliquots or large-volume production batches, CamelBio bridges your concept to clinic with reliable supply and technical support.