Anti-Human CD7 Monoclonal Antibody (Biotin) for Flow Cytometry - P09564

Core Product Specifications and Parameters

Biological Background: CD7 Function and Localization

• CD7 (also known as GP40, TP41, Leu-9) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily.
• Functions as a costimulatory receptor in T-cell activation upon binding to its ligand K12/SECTM1. Related references: PMID:10652336
• Promotes production of cytokines such as IL-2. Related references: PMID:1709867
• On resting NK cells, CD7 activation induces interferon-gamma secretion. Related references: PMID:7506726
• Subcellular localization: membrane (single-pass type I membrane protein).
• Tissue specificity: expressed on T-cells, NK cells, and their precursors.
• Keywords include adaptive immunity, disulfide bond, glycoprotein, immunoglobulin domain, lipoprotein, palmitate, reference proteome, repeat, signal, transmembrane helix.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the extracellular domain (aa 26-180), making this antibody suitable for flow cytometry applications to detect cell surface CD7.
• Biotinylation enables flexible detection with streptavidin conjugates; consider optimizing the concentration and staining protocol for your specific cell types.
• Validate in relevant sample systems (e.g., human PBMCs) to confirm specificity for T-cell and NK cell subsets.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. This CD7 antibody supports T-cell and NK cell research, offering validated and optimized monoclonal antibodies. Our B2B supply capabilities include antibody pairs, bulk ancillary reagents, and rare target raw-material sourcing to streamline your development pipeline.