Anti-HOXD10 Polyclonal Antibody for WB, ELISA - P28358

Core Product Specifications and Parameters

Biological Background: HOXD10 Function and Localization

• HOXD10 (Homeobox protein Hox-D10), also known as Hox-4D, Hox-4E, or Hox-4.4, is encoded by the HOXD10 gene in humans.
• It is a sequence-specific transcription factor that plays a key role in anterior-posterior axis specification during development.
• Belongs to the homeobox protein family, characterized by a conserved DNA-binding homeodomain.
• Localizes to the nucleus, consistent with its role in transcriptional regulation.
• Strongly expressed in adult male and female urogenital tracts, indicating tissue-specific functions.
• Classified as a developmental protein and is a reference proteome member; subject to phosphorylation and other post-translational modifications.
• Associated with disease variants, highlighting its clinical relevance in developmental disorders.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the full-length human HOXD10 protein (amino acids 1-240); polyclonal antibodies may recognize multiple epitopes, enhancing detection sensitivity.
• For WB, validate the antibody in your sample system; endogenous HOXD10 has a predicted molecular weight of approximately 38 kDa.
• Cross-reactivity with mouse and rat is indicated; consider testing in these species after verifying sequence homology.
• In ELISA, use the antibody as a capture or detection reagent; optimal dilution should be determined experimentally.
• Consider using nuclear extracts or fractionated lysates to enrich for the target protein.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers comprehensive IVD raw material sourcing and technical services to support diagnostic manufacturers and research laboratories. For HOXD10-related studies in developmental biology and urogenital diseases, we provide validated antibody pairs, optimized polyclonal and monoclonal antibodies, and bulk ancillary reagents. Our one-stop platform streamlines procurement from early-stage R&D to clinical application, including rare target sourcing and custom production.